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T-CELL LEUKAEMIA VIRUSES

Group of retroviruses which infect T-lymphocytes and cause leukaemias. Some cause malignant transformation of T-lymphocytes eg HTLV-1 or feline leukaemia virus whereas others cause AIDS HTLV-3, now renamed HIV for human immuno

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T-CELL REPLACING FACTOR

A soluble factor derived from helper T-lymphocytes which can replace the presence of T-lymphocytes in stimulating antibody production by B- lymphocytes which have been activated by antigen. Synonymous with B-cell differentiation factors of which one is identified as interleukin-4.

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T-DISTRIBUTION

The sampling distribution of the mean of a set of observations from a normal distribution with unknown variance. The central t-distribution has one parameter, the degrees of freedom, and describes the sampling distribution of the deviation of the sample mean from the population mean.

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T-GAUGE

Type of marking gauge with long marker pin and large flat fence; used for marking jobs where mould

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T-GRAIN

Silver halide grains in tablet form, offering greater area and hence greater sensitivity in a photographic emulsion.

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T-HELPER CELL

T-lymphocytes of the CD4+ve subset which provide 'help' in the form of interleukins to other lymphocytes allowing them to differentiate to perform their immune effector functions. This subset is attacked by the HIV virus and is severely depleted in AIDS patients. See panel on Acquired immunodeficiency syndrome AIDS

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T-IRON

A structural member of wrought-iron or rolled mild steel having a T-shaped cross-section,

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T-LYMPHOCYTE ANTIGEN RECEPTOR

T

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T-LYMPHOCYTE REPERTOIRE

The number of different antigenic determinants to which the T-lymphocytes of an individual animal are capable of responding, thought to be comparable in size to the B-lymphocyte repertoire. There are however certain peptide sequences which are not recognized, either because they are not recognizably different from

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T-MAZE

A T-shaped pathway with a starting box at the base of the T and goal boxes containing reinforcing stimuli at the ends of either or both arms. Discriminative stimuli may be placed in the arms of the T near the choice point.

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