What is V-GENE?

That coding for the variable region of immunoglobulin heavy or light chain. It is widely separated from the C-gene constant region in germ line DNA as present in lymphocyte precursors and other body cells such as in liver, but during maturation of B lymphocytes it is rearranged by translocation to a position close to the 5' end of the C-gene, but still separated from it by an intron. A similar process takes place during the maturation of T lymphocytes,


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