What is HLA-A, HLA-B, HLA-C?

Histocompatibility antigens, each coded by different loci in the MHC genes, and for which there are numerous allelic products at each locus. These antigens belong to Class I and have similar structures, consisting of a membrane-bound polypeptide to which is attached non-covalendy /i2 microglobulin. Class I antigens are present on almost all nucleated cells. Cytotoxic T cells recognize antigens in association with Class I molecules.


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